Ion Homeostasis Channels in Middle Ear Inflammation
نویسندگان
چکیده
منابع مشابه
Mouse Middle Ear Ion Homeostasis Channels and Intercellular Junctions
HYPOTHESIS The middle ear contains homeostatic mechanisms that control the movement of ions and fluids similar to those present in the inner ear, and are altered during inflammation. BACKGROUND The normal middle ear cavity is fluid-free and air-filled to allow for effective sound transmission. Within the inner ear, the regulation of fluid and ion movement is essential for normal auditory and ...
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The inner and middle ear are connected mainly through round and oval windows, and inflammation in the middle ear cavity can spread into the inner ear, which might induce a disturbance. In cases with intractable otitis media, attention should also be paid to symptoms related to the inner ear. In this paper, middle ear inflammation and related inner ear disturbances are reviewed with a focus on r...
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HYPOTHESIS Transtympanic steroid treatment will induce changes in ion homeostasis and inflammatory gene expression to decrease middle ear inflammation due to bacterial inoculation. BACKGROUND Otitis media is common, but treatment options are limited to systemic antibiotic therapy or surgical intervention. Systemic glucocorticoid treatment of mice decreases inflammation and improves fluid clea...
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Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by widespread inflammation, focal demyelination and a variable degree of axonal and neuronal loss. Ionic conductances regulate T cell activation as well as neuronal function and thus have been found to play a crucial role in MS pathogenesis. Since present therapeutical approaches are only parti...
متن کاملCholesteatoma – A Potential Consequence of Chronic Middle Ear Inflammation
While the middle ear is the most typical localization, ectopic cholesteatoma has been described for many sites, including the mastoid process [5], the petrous bone [6-8], the external auditory canal [9-14], the paranasal sinuses [15-17] with special emphasis on the frontal sinus [18-19], the genitourinary tract [20] including the ureter [21-23], the renal pelvis [21], the pyelocaliceal region [...
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ژورنال
عنوان ژورنال: Otolaryngology–Head and Neck Surgery
سال: 2010
ISSN: 0194-5998,1097-6817
DOI: 10.1016/j.otohns.2010.06.518